We focus on the lung brain axis and the gut brain axis and the HPA axis. We grow pulmonary neuroendocrine cells and characterize their role in asthma and the neuro-dysfunction that occurs due abnormal behaviour of PNECS. We are also looking the effect of Asthma on inflammation in the brain and stress disorders, depression, anxiety and other mood disorders.
Our lab addresses cross-talk between components of the immune and nervous systems, and how such communication may influence the development of diverse pathophysiological responses such as inflammation, allergy and mood disorders.
May 25, 2023
Dr. Ritu Mann-nuttel, our post-doc was awarded the Paul Man Award for her work, "House dust mite allergen induces PAR-1 dependent CGRP release from cultured human pulmonary neuroendocrine cells"
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June 26, 2023
Great news! Dr. Ritu Mannuttel was once again awarded best oral presentation for her work on "Response of human pulmonary neuroendocrine cells to house dust mite allergen" at the annual Immunet Research Symposium held at University of Alberta.
April 1, 2023
Good news! The Forsythe lab has been awarded an Allergic Airways Disease Innovation Grant
by CIHR-ICRH and the Canadian Allergy, Asthma, and Immunology Foundation (CAAIF) for the project
“Pulmonary Neuroendocrine Cells as targets for gene therapy in asthma”